Scaffold materials used in bone tissue engineering include a scaffold and a matrix. Methods of preparing scaffold materials include the identification of the biodegradation characteristics of the scaffold and matrix. Construct a skeleton to form a three-dimensional shape. The scaffold is constructed from a first material and has a first biodegradation rate. The base material is filled in a three-dimensional shape formed by the skeleton. The matrix is constructed from a second material and has a second biodegradation rate. The first biodegradation rate is less than the second biodegradation rate.骨組織工学で用いられる足場材料は、骨格と母材を含む。足場材料を調製する方法は、骨格と母材の生分解特性の同定を含む。骨格を構築して三次元形状を形成する。骨格は第一の材料から構築され、第一の生分解速度を持つ。骨格により形成された三次元形状に母材を充填する。母材は第二の材料から構築され、第二の生分解速度を持つ。第一の生分解速度は、第二の生分解速度よりも小さい。