Novel anti-human IL-23 receptor antibody

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专利权人:

アステラス製薬株式会社

发明人:

米澤 敦夫,大堀 誠,佐々木 孝則,佐藤 照,田口 克成

申请号：

JP2014502301

公开号：

JP6137169B2

申请日:

2013.02.27

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

[Problem] An object of the present invention is to provide an anti-human IL-23R antibody having excellent activity and/or cross-reactivity compared to conventional IL-23R antibodies, and means for using the antibody to prevent or treat various diseases such as ophthalmic disease, inflammatory bowel disease, or psoriasis in which human IL-23R is involved in pathogenesis. [Means for Solution] An anti-human IL-23R antibody comprising a heavy-chain variable region consisting of the amino acid sequence shown by SEQ ID NO: 10 or 14 and a light-chain variable region consisting of the amino acid sequence shown by SEQ ID NO:6 or 18.

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