The disclosure provides a foldable portable excrement pick-up device. The device includes an upper housing and a lower housing which are combined to form a clip shape via a rotary shaft and a spring. The upper housing is composed of an upper handle and a cap-shaped upper housing body. The lower housing is composed of a lower handle and a bowl-shaped lower housing body. The upper handle and the lower handle are symmetrically arranged, the upper housing body and the lower housing body are hinged to form a clip shape in such a way that the rotary shaft penetrates through the upper hinging portion and the lower hinging portion, and the spring is arranged between the upper handle and the lower handle to make the upper housing body cover the lower housing body elastically in an openable/closeable manner.