HUMAN CYTOMEGALOVIRUS NEUTRALISING ANTIBODIES AND USE THEREOF

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专利权人:

INSTITUTE FOR RESEARCH IN BIOMEDICINE

发明人:

ANTONIO LANZAVECCHIA,ANNALISA MACAGNO

申请号：

PT08875708

公开号：

PT2303923E

申请日:

2008.07.16

申请国别(地区):

PT

年份:

2015

代理人:

摘要：

The invention relates to neutralising antibodies which are specific for human cytomegalovirus (hCMV), specifically the antibodies of the invention are specific for a combination of the hCMV proteins UL128, UL130 and UL131A. Antibodies of the invention neutralise infection with high potency. The invention also relates to immortalised B cells that produce such antibodies, to the epitope that the antibodies bind to as well as the use of the antibodies and the epitope in screening methods as well as the diagnosis and therapy of disease.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/