Device and method for lasering biological tissue. In a general aspect, the device for lasering a biological tissue may include a source configured to provide a pulsed laser beam, an outcoupler configured to couple the laser beam towards the tissue, and an outfeeder configured to feed a photosensitizer in a direction of the tissue where the outfeeder is connected to the outcoupler. In another general aspect, a method for lasering a biological tissue may include applying a photosensitizer towards the tissue, providing a pulsed laser beam, and lasering a site of the tissue with the pulsed laser beam where the laser beam is emitted with a temporal width at a half maximum range from about 1 ps to about 100 ps.
