Paul Renhowe;Qiang Ding;Chengzhi Zhang;Daniel Poon;Pamela Albaugh;Shifeng Pan;Xing Wang;Qiong Zhang;Pingda Ren;Martin S;Gregory B. Chopiuk;Xia Wang;Guobao Zhang;Shenlin Huang;Yongping Xie;Zuosheng Liu
发明人:
Pamela Albaugh,Gregory B. Chopiuk,Qiang Ding,Shenlin Huang,Zuosheng Liu,Shifeng Pan,Pingda Ren,Xia Wang,Xing Wang,Yongping Xie,Chengzhi Zhang,Qiong Zhang,Guobao Zhang,Daniel Poon,Paul Renhowe,Martin S
申请号:
US12444129
公开号:
US08202876B2
申请日:
2007.09.24
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, ARG, BCR-Abl, BRK, EphB, Fms, Fyn, KDR, c-Kit, LCK, PDGF-R, b-Raf, c-Raf, SAPK2, Src, Tie2 and TrkB kinases.