Chengzhi Zhang,Daniel Poon,Gregory S. Chopiuk,Guobao Zhang,Martin Sendzik,Pamela A. Albaugh,Paul Renhowe,Pingda Ren,Qing Ding,Qiong Zhang,Shenlin Huang,Shifeng Pan,Xia Wang,Xing Wang,Yongping Xie,Zuos
申请号:
BRPI0719797
公开号:
BRPI0719797A2
申请日:
2007.09.24
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, ARG, BCR-Abl, BRK, EphB, Fms, Fyn, KDR, c-Kit, LCK, PDGF-R, b-Raf, c-Raf, SAPK2, Src, Tie2 and TrkB kinases.