SALTS OF (S)-4-[(R)-6-(2-CHLORO-4-FLUORO-PHENYL)-5-METHOXYCARBONYL-2-THIAZOL-2-YL-3,6- DIHYDRO-PYRIMIDIN-4-YLMETHYL]-MORPHOLINE-3-CARBOXYLIC ACID, SALT FORMER AND METHODS FOR PREPARING AND USING THE SAME
The present invention relates to salts of (S)-4-[(R)-6-(2-Chloro-4-fluoro-phenyl)-5- methoxycarbonyl-2-thiazol-2-yl-3,6-dihydro-pyrimidin-4-ylmethyl]-morpholine-3-carboxylic acid and an acid, the synthesis of the acid salts, and their use for the treatment of pathological disorders, particularly hepatitis B (HBV) infection.La présente invention concerne des sels dacide (S)-4-[(R)-6-(2-chloro-4-fluoro-phényl)-5-méthoxycarbonyl-2-thiazol-2-yl-3,6-dihydro-pyrimidin-4-ylméthyl]-morpholine-3-carboxylique et un acide, la synthèse des sels dacide, et leur utilisation pour le traitement de troubles pathologiques, en particulier linfection par le virus de lhépatite B (VHB).
