A specimen retrieval device (600) includes a handle (601), a shaft (603) connected to said handle, and a bag deployment device (605) connected to a distal end of the shaft. A specimen retrieval bag (607) is connected to the bag deployment device and includes at least one material having a mesh (608) disposed therein. At least one strand of the mesh is disposed at an angle (609) relative to the bag deployment device and the flexibility of the bag is a function of the angle.