Antagonists of dsg2 for treatment of cancer

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专利权人:

ASCLEPIUMM LIMITED

发明人:

CHEN MIN-CHE

申请号：

NZ59904910

公开号：

NZ599049A

申请日:

2010.09.22

申请国别(地区):

NZ

年份:

2014

代理人:

摘要：

599049 Disclosed is a monoclonal antibody as an antagonist for use as a medicament for preventing or treating cancer, wherein the monoclonal antibody specifically binds to the amino acid sequence: TQDVFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYR, KINATDADEPNTLNSKISYR or EELSAAHTLV of the non-cell adhesion recognition (CAR) sites region of the EC2 domain of Dsg2 and inhibits epithelial mesenchymal transition (EMT).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/