Hydroxyindole carboxylic acid based inhibitors for oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2)

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专利权人:

发明人:

Zhong-Yin Zhang,Li-Fan Zeng

申请号：

US14786621

公开号：

US09522881B2

申请日:

2014.04.25

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Inhibitors of protein tyrosine phosphatases are disclosed. The inhibitors include hydroxyindole carboxylic acids having a linker and an amine scaffold that are potent inhibitors of Src homology 2-domain containing protein tyrosine phosphatase-2.

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