INHIBITEURS À BASE D'ACIDE CARBOXYLIQUE D'HYDROXYINDOLE POUR DOMAINE D'HOMOLOGIE AVEC LA PROTÉINE SRC 2 ONCOGÈNE CONTENANT LA PROTÉINE TYROSINE PHOSPHATASE-2 (SHP2)
Indiana University Research & Technology Corporation
发明人:
申请号:
EP14788844.0
公开号:
EP2988741B1
申请日:
2014.04.25
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
Inhibitors of protein tyrosine phosphatases are disclosed. The inhibitors include hydroxyindole carboxylic acids having a linker and an amine scaffold that are potent inhibitors of Src homology 2-domain containing protein tyrosine phosphatase-2.