THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY
发明人:
申请号：
EP07874490.1
公开号：
EP2086526B1
申请日:
2007.11.02
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
The invention relates to a method of inducing an immune response to dengue virus comprising administering a priming dengue virus immunogen and boosting with a heterologous dengue virus immunogen wherein: a. said priming dengue virus immunogen is selected from the group consisting of: i) a DNA expression system； ii) an adenovirus expression vector； and iii) a Venezuelan equine encephalitis virus replicon system； b. said boosting dengue virus immunogen is selected from the group consisting of: i) an adenovirus expression vector； and ii) a Venezuelan equine encephalitis virus replicon system.
