The United States Of America As Represented By The Secretary Of The Navy
发明人:
申请号:
EP12001416.2
公开号:
EP2462930B1
申请日:
2007.11.02
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The invention relates to a method of inducing an immune response to dengue virus comprising administering a priming dengue virus immunogen and boosting with a heterologous dengue virus immunogen wherein: a. said priming dengue virus immunogen is selected from the group consisting of: i) a DNA expression system; ii) an adenovirus expression vector; and iii) a Venezuelan equine encephalitis virus replicon system; b. said boosting dengue virus immunogen is selected from the group consisting of: i) an adenovirus expression vector; and ii) a Venezuelan equine encephalitis virus replicon system.