William F. Goure,Franz F. Hefti,Renee C. Gaspar,Paul J. Shughrue,Fubao Wang,Weirong Wang,Ningyan Zhang,Wei-Qin Zhao
申请号：
US14648316
公开号：
US20150320860A1
申请日:
2013.12.04
申请国别(地区):
US
年份:
2015
代理人:
摘要：
This invention is a method and kit for treating a disease associated with, or resulting from, the accumulation of soluble oligomer amyloid beta 1-42 using an antibody, or antibody fragment thereof, that has a higher affinity for amyloid beta 1-42 oligomers than for amyloid beta 1-42 monomer, amyloid beta 1-40 monomer, plaques and amyloid beta fibrils, wherein the antibody is in combination with a tau therapeutic or an inhibitor of amyloid beta production or aggregation.
