Consejo Nacional de Investigaciones Científicas y Técnicas;Northwestern University;Universidade Federal do Rio de Janeiro
发明人:
William L. Klein,Diana Jerusalinsky,Sergio T. Ferreira,Maria Clara Selles,Adriano S. Sebollela
申请号：
US16820269
公开号：
US20200289589A1
申请日:
2020.03.16
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein are antibodies against amyloid-beta (Aβ) oligomers, and methods of use thereof for the treatment of Alzheimer's disease (AD). In particular, neauronal expression of single-chain variable fragment (scFv) antibodies against Aβ oligomers is provided as a therapeutic approach in the treatment of AD.
