Emma Jane Kidd,Janet Eryl Liddell,Rhian Sara Thomas
申请号：
US12739599
公开号：
US08337848B2
申请日:
2008.10.23
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to a novel peptide, polypeptide or monoclonal antibody for use in the treatment of conditions characterized by elevated levels of β-amyloid (Aβ 39-43 amino acid peptide) in a subject, especially Alzheimers Disease. The invention particularly relates to an amyloid precursor protein (APP)-binding polypeptide which, when administered outside an APP-expressing cell, reduces the release of Aβ 39-43 by the cell.
