A control system for a thermo-regulation assembly, which includes: a fluid manifold assembly (12 ') that includes a manifold inlet for receiving thermo-regulating fluid from at least one source of thermo-regulating fluid to a thermo-regulation temperature, and a manifold outlet (26) for supplying thermo-regulating fluid to an interface package； wherein the manifold assembly is operable to selectively provide thermal regulation fluid to said interface package through the manifold outlet according to the feed parameters； an operable control unit (56 ') to obtain a characteristic energy transfer rate between a first user and a first interface package of this type before the start of a treatment plan, and to obtain a desired temperature profile and a conversion algorithm, in which the desired temperature profile provides a temperature profile of the desired interface package over time for the treatment plan and the conversion algorithm provides a formula to derive one or more feed parameters to make that the first interface package reaches or maintains a desired temperature, on which the conversion algorithm depends on the characteristic energy transfer rate； wherein the control unit (56 ') is operable to calculate one or more feed parameters from the desired temperature profile and the conversion algorithm； wherein the control unit (56 ') is operable to operate the fluid manifold assembly according to said one or more feed parameters； wherein the characteristic energy transfer rate is a difference between an absolute energy transfer rate of the first interface packet when it is applied to the first user, and an energy transfer rate of the first interface packet without a user.Un sistema de control para un conjunto de termo-regulación, que incluye: un conjunto (12') de colector de fluido que incluye una entrada de colector para recibir fluido de termo-regulación desde al menos una fuente de fluido de termo-regulación a una temperatura de termo-regulación, y una salida (
