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Nucleic acid for plant expression of a fusion protein comprising hydroxyproline O-glycosylation glycomodule
专利权人:
Marcia J. Kieliszewski;Jianfeng Xu;Gary D. Meyer
发明人:
Marcia J. Kieliszewski,Jianfeng Xu,Gary D. Meyer
申请号:
US13019819
公开号:
US09006410B2
申请日:
2011.02.02
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Methods of increasing the yield in plant expression of recombinant proteins comprising engineering glycosylation sites into cloned genes or cDNAs for proteins using codons that drive post-translational modifications in plants and engineering the cloned genes or cDNAs to contain a plant secretory signal sequence that targets the gene products (protein) for secretion are present. The methods result in increased recombinant glycosylated protein yields. Proteins produced according to these methods are also present.
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