A method and apparatus for disrupting material at a tissue site is described. The apparatus includes a modulating layer formed from an open-cell reticulated foam and positionable adjacent the tissue site. The apparatus also includes a macro-column layer formed from a felted foam and having a plurality of through-holes separated from each other by walls. The macro-column layer is positionable adjacent to the modulating layer. The through-holes form nodules in the tissue site in response to negative pressure.
