This disclosure provides an optical fiber puncture needle tubing and the use thereof. the puncture needle tubing comprises an optical fiber comprising a body portion and a head portion, in which the forefront end of the tapered head is a tapered tail end having a tapered diameter formed by a taper method; the periphery of the body portion is wrapped with a body tube, the cylindrical head is wrapped with a metal casing, and the periphery of the tapered head is wrapped with a polymer jacket; in which in the polymer jacket, the part thereof corresponding to the tapered tail end is a taper structure wrapped around the tapered tail end and having a tapered diameter; the polymer jacket is provided with an inverted-tooth structure or inverted kerf structure. Through the synergistic effect with various components, the puncture needle tubing can be transmitted fast in the long blood vessels, and can achieve higher light emission efficiency and therapeutic effect, so that it has important application value and significance in the treatment of photodynamic tumors. In addition, the puncture needle tubing also can be applied in other fields, such as eliminating vascular obstructions or performing vascular puncture, etc.