Hitesh Handa,Mark E. Meyerhoff,Robert H. Bartlett,Elizabeth J. Brisbois,Lahdan Refahiyat
申请号：
US14430545
公开号：
US09566372B2
申请日:
2013.09.25
申请国别(地区):
US
年份:
2017
代理人:
摘要：
A polymeric composition includes a polymer matrix having a lipophilic discrete nitric oxide adduct and/or a polymeric nitric oxide adduct associated therewith, by covalent attachment to the polymer matrix and/or by dispersion within the polymer matrix, with the discrete nitric oxide adduct and/or the polymeric nitric oxide adduct being capable of releasing nitric oxide (NO). The polymeric composition further includes an ester capped poly(lactide-co-glycolide) (PLGA) additive to at least one of increase, prolong, and control NO release rates from the lipophilic discrete nitric oxide adduct and/or the polymeric nitric oxide adduct.
