A device having a first stimulation unit that generates electrical first stimuli suppressing a pathological synchronous activity of neurons in the brain and/or spinal cord of a patient upon administering the same to the brain and/or spinal cord of the patient, a second stimulation unit that generates optical and/or acoustic and/or tactile and/or vibratory second stimuli, and a controller that controls the first and the second stimulation units. The generation of the first and second stimuli optionally occurs in a first or in a second operating mode, and the controller actuates the first and the second stimulation units such that in the first operating mode the generation of at least 60% of the second stimuli is chronologically coupled to the generation of the first stimuli, and in the second operating mode the generation of at least 60% of the second stimuli is carried out without generating the first stimuli.