A radiation irradiation system includes a radiation irradiation device and a treatment bed for transporting a target to be irradiated, the treatment bed has a positioning assembly. The positioning assembly includes a shielding body and a sealing bag for accommodating the shielding body. The shielding body includes silicone and a radiation shielding material which is capable of shielding radiation. After the positioning assembly with the target to be irradiated is placed on the surface of the sealing bag is vacuumized, the positioning assembly is recessed with a shape of the target to at the position where the target to be irradiated is placed and forms a contour as the target to position the target. The positioning assembly is provided to position the target to avoid therapeutic effect caused by the movement of the target during the irradiation therapy, and avoid radioactive damages to the target except for the parts on which irradiation therapy needs to be performed, and to medical staff during the radiation irradiation therapy.輻射線照射系統包括輻射線照射裝置及將被照射體運輸至所述輻射線照射裝置進行照射的治療床，所述治療床具有定位組件，所述定位組件包括屏蔽體以及容置所述屏蔽體的密封袋，所述屏蔽體包括矽膠和能夠對輻射線進行屏蔽的輻射線屏蔽材，當對密封袋表面置有被照射體的定位組件抽真空後，所述定位組件置有被照射體的位置隨著被照射體的形狀凹陷形成與所述被照射體相同的輪廓以對所述被照射體進行定位。通過設置定位組件對被照射體進行定位，以避免因被照射體在照射治療過程中發生運動而導致治療效果的差異，同時避免了在輻射線照射治療過程中輻射線對被照射體需要進行輻射治療以外的部位及醫護人員造成輻射傷害。
