The present invention relates to a radiofrequency (RF) hyperthermia device for personalized treatment and diagnosis using capacitive coupling and without dipole antenna comprising a radiofrequency source, an amplifier, a sensor and a modulation signal input/generator, wherein the radiofrequency source produces a source signal which is modulated by the modulation signal input/generator using the phase information generated by homeostasis of the target to generate a modulated source signal, the modulated source signal is amplified by the amplifier and directed to a target, and the sensor detects the phase information generated by homeostasis of the target to provide a feedback signal, wherein the feedback signal modulates the source signal to generate a personalized modulated signal. This radiofrequency (RF) hyperthermia device is designed for personalized treatment and diagnosis of a target such as a patient or a malignant or tumorous area within a patient.
