The present invention relates to a radiofrequency (RF) hyperthermia device comprising a radiofrequency source, an amplifier, a sensor, a feedback amplifier and a modulation signal generator, wherein the radiofrequency source produces a source signal which is modulated by the modulation signal generator, amplified by the amplifier and directed to a target, the sensor receives a feed back signal from the target that is directed to the feed back amplifier, wherein the feedback signal is amplified by the feedback amplifier and modulates the source signal to generate a target modified signal. This radiofrequency (RF) hyperthermia device is designed for increasing the selectivity of the hyperthermia treatment.