Disclosed is a composition comprising the reaction product of: (a) an isocyanate group-containing component having an average functionality of at least 2； selected from the group consisting of lysine diisocyanate and esters thereof, lysine triisocyanate and esters thereof, and combinations thereof: and (b) an active hydrogen group-containing component having an average functionality of at least 2, comprising (i) at least one poly-hydroxy functional compound selected from the group consisting of polyether polyols, polyester polyols, and polyhydroxyalkyl derivatives of C3-C10 hydrocarbons and (ii) at least one monohydroxy functional compound selected from the group consisting of hydroxyalkylamines and alkyl alcohols； wherein the composition is biodegradable, a solid at 22°C and below, and has pressure sensitive adhesive properties at a temperature of 37°C and relative humidity of 100%.
