A method of making a composition comprising reacting (a) an isocyanate group-containing component having an average functionality of at least 2 and (b) an active hydrogen group-containing component having an average functionality of at least 2 to form a composition that is biodegradable, a solid at 22° C. and below, and has pressure sensitive adhesive properties at a temperature of 37° C. and relative humidity of 100%. A method of using the composition therefore to adhere polymer meshes or films to biological tissue is also disclosed.
