Methods and systems of patient treatment are disclosed. The methods and systems include use of medical device informatics to modify and validate therapies and drugs used in those therapies. In certain embodiments, a medical device, such as a medical infusion pump, interfaces with a server to administer the patient treatments. In one such embodiment, a method for use of metadata on medical devices is disclosed. A method includes associating metadata with one or more medical devices, the metadata corresponding to an attribute of the medical devices. The method also includes storing the metadata on a server, the server configured to communicate with each of the medical devices by using the metadata.