A medication storage structure is provided. The medication storage structure has a container, a lid and a locking device. Within the container a first storage region and a second storage region are defined. The inner surface of the second storage region has a positioning unit. The lid has an upper surface and a lower surface, and a fastener with a through hole is disposed on the lower surface. Further, the locking device is disposed in the second storage region and slidably connected with the positioning unit. A latch tongue of the locking device selectively insert into the through hole in order to firmly lock the lid.本創作為一藥盒結構,該藥盒結構包含一盒體、一上蓋及一鎖扣裝置。盒體定義有一第一容置空間及一第二容置空間,且第二容置空間的一內壁上設置有一定位單元。上蓋則具有一上表面及一下表面。下表面於對應第二容置空間設置有一卡扣件,且卡扣件具有一貫穿孔。鎖扣裝置則設置於盒體之第二容置空間中。鎖扣裝置與定位單元可滑動地相連接,並利用鎖扣裝置之一鎖舌選擇地插置於卡扣件之貫穿孔中,以穩固地鎖扣上蓋。11b‧‧‧第二容置空間112‧‧‧定位單元12‧‧‧上蓋121‧‧‧卡扣件13‧‧‧鎖扣裝置131‧‧‧軌道、第一軌道、第二軌道14‧‧‧感測單元