Composés contenant de l'azote et leurs compositions pharmaceutiques pour le traitement de la fibrillation auriculaire

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专利权人:

OTSUKA PHARMACEUTICAL CO.; LTD.

发明人:

申请号：

EP14153417.2

公开号：

EP2727917A1

申请日:

2010.08.20

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The present invention provides a novel amino compound that blocks the IKur current or the Kv1.5 channel potently and more selectively than other K+ channels. The present invention relates toa benzodiazepine compound represented by General Formula (1):or a salt thereof,wherein R1, R2, R3, and R4 are each independently hydrogen or lower alkyl； R2 and R3 may be linked to form lower alkylene；A1 is lower alkylene optionally substituted with one or more hydroxyls； and R5 is an aryl or heterocyclic group, each of which is optionally substituted.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/