The purpose of the present invention is to provide: a simple method by which a porous substrate comprising a bioabsorbable polymer that contains heparin is produced without the use of surfactants a porous substrate comprising a bioabsorbable polymer that contains heparin and an artificial blood vessel. The present invention is a method for producing a porous substrate comprising a bioabsorbable polymer that contains heparin, said method including: a solution preparation step in which a heparin-bioabsorbable polymer solution containing uniformly dispersed heparin and a dissolved bioabsorbable polymer is prepared using a biabsorbable polymer, heparin, a solvent 1 which is a poor solvent having low solubility with respect to the bioabsorbable polymer, a solvent 2 which is a good solvent having high solubility with respect to the bioabsorbable polymer and which is not miscible with the first solvent 1, and a cosolvent 3 which is miscible with the first solvent 1 and the second solvent 2 a precipitation step in which the heparin-bioabsorbable polymer solution is cooled and a porous material comprising bioabsorbable polymer that contains heparin is precipitated and a freeze drying step in which the porous material comprising bioabsorable polymer that contains heparin is freeze dried in order to obtain a porous substrate containing heparin.Le but de la présente invention est de fournir : un procédé simple par lequel un substrat poreux comprenant un polymère bioabsorbable qui contient de lhéparine est produit sans utiliser de tensioactifs un substrat poreux comprenant un polymère bioabsorbable qui contient de lhéparine et un vaisseau sanguin artificiel. La présente invention concerne un procédé de production dun substrat poreux comprenant un polymère bioabsorbable qui contient de lhéparine, ledit procédé comprenant: une étape de préparation de solution dans laquelle une solution de polymère bioabsorbable à lhéparine contenant de lhéparine uniformément dispersée et un polymè
