The purpose of the present invention is to discover a pharmaceutical preparation which is for treating or preventing glaucoma or intraocular hypertension and exhibits effects on a patient in which the efficacy of a therapeutic agent for glaucoma or intraocular hypertension is insufficient. It is found that omidenepag, an ester thereof, or a salt thereof is proven to exhibit an excellent intraocular tension depressive action on a patient in which the efficacies of other therapeutic agents for glaucoma or intraocular hypertension are insufficient. Therefore, omidenepag, an ester thereof, or a salt thereof according to the present invention is useful as a pharmaceutical preparation capable of treating or preventing glaucoma or intraocular hypertension even on a patient in which the efficacies of other therapeutic agents for glaucoma or intraocular hypertension are insufficient.本發明之目的在於發現一種醫藥製劑，其對青光眼或高眼壓症治療藥效果不充分之患者顯示效果，用以治療或預防青光眼或者高眼壓症。由本發明可知：奧米帕格或者其酯或其等之鹽對其他青光眼或高眼壓症治療藥效果不充分之患者顯示優異之眼壓下降作用。因此，本發明之奧米帕格或者其酯或其等之鹽作為對其他青光眼或高眼壓症治療藥效果不充分之患者亦可治療或預防青光眼或者高眼壓症的醫藥製劑有用。
