PROBLEM TO BE SOLVED: To provide an oral solid tablet which has high dispersibility in a body, and reduction of tablet hardness with time is suppressed.SOLUTION: An oral solid tablet of the present invention contains: granulation particles (A) containing a poorly water-soluble drug (a1) with 5 mg/mL or less of solubility to water at 20°C, one kind or more of a polymeric compound (a2) selected from the group consisting of a water-swellable polymeric compound with 1000 or more of molecular weight and a water-soluble polymeric compound with 1 mg/mL or more of solubility to water at 20°C and molecular weight of 1000 or more, and water-soluble powder (a3) (excluding particles (B) below) with higher than 5 mg/mL of solubility to water at 20°C and molecular weight of less than 1000 and particles (B) made of one kind or more of a compound selected from the group consisting of hydrogen carbonate and carbonate.COPYRIGHT: (C)2016,JPO&INPIT
