Pharmaceutical compositions containing these Compounds, and these compounds for use in the prophylaxis and / or treatment of Pain and other diseases and / or conditions.Claim 1: a substituted Compound of General formula (1) wherein r u00b9 represents a residue c u2082 u208b u2086 without replacing or aliphatic, mono or polisustituido； or a cicloalif u00e1tico c u2083 u208b u2086 residue or residue heterocicloalif u00e1tico 3 to 6 members, in each case without replacing Polisustituido or mono or, and in each case by a c u2081 u208b u2084 optionally bridged aliphatic Group,That in turn can be without replacing or mono or polisustituido represents or u2076； or, where r u2076 represents a residue c u2081 u208b u2086 without replacing or aliphatic, mono or polisustituido； or a residue cicloalif u00e1tico c u2083 u208b u2086, without replacing or mono or polisustituido； R u00b2 and r u00b3 regardless of each Vehicle To represent h, F, CL, BR, i) ch u2082f chf u2082；；；； cf u2083； Oh； och u2082f； ochf u2082； ocf u2083 scf u2083； residue； aliphatic c u2081 u208b u2084,Residue or an aliphatic or aliphatic residue c u2081 u208b u2084, where the c u2081 u208b u2084 can in each case be without replacing or mono or polisustituido； or a cicloalif u00e1tico c u2083 u208b u2086 residue or residue heterocicloalif u00e1tico 3 to 6 members,In each case, without replacing or mono or polisustituido； provided that at least one of R u00b2 and r u00b3 indicates H o is linked through a carbon Atom； r u2074 and r u2075 regardless of which each represents h； ch u2082f； chf u2082 cf u2083； residue； aliphatic c u2081 u208b u2084,Where The residue can be c u2081 u208b u2084 without replacing or aliphatic mono or polisustituido； or a cicloalif u00e1tico c u2083 u208b u2086 residue or residue heterocicloalif u00e1tico 3 to 6 members, in each case without replacing or mono or polisustituido； provided if r u2074 and / or r u2075 indicates a residue het (n) Erocicloalif u00e1tico 3 to 6 members,The
