Peg-albumin composition having at least one protected thiol region as a platform for medications

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专利权人:

Ragheb Assaly

发明人:

Ragheb Assaly,John David Digman,Joseph I Shapiro

申请号：

US13138558

公开号：

US20120010144A1

申请日:

2010.04.02

申请国别(地区):

US

年份:

2012

代理人:

摘要：

This composition comprises a polyethylene glycol-albumin composition having at least one protected thiol region wherein the composition comprises PEG-AlbCys34 with Cys-34 preserved as a thiol. The albumin is linked to medications such as, antioxidants with a reduced sulfhydryl group through the Cys 34 residing on the albumin. The compositions are useful in treating patients.

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