ZHUHAI HAI BIN PHARMACEUTICAL BIOTECHNOLOGY CO.; LTD.
发明人:
KONG XIANGSHENG
申请号:
NL2012394
公开号:
NL2012394C2
申请日:
2014.03.11
申请国别(地区):
NL
年份:
2015
代理人:
摘要:
The present invention relates to a novel broad-spectrum antifungal compound and a broad-spectrum antifungal composition, comprising 3-methyl-1-[[6-(1H-pyrrol-yl)-2-methanesulfonyl-1-phenyl] benzothiazole ]-1Hpyrrole-2ol. The compound or composition can be used in the preparation of broadspectrum antifungal agents for the treatment of severe invasive aspergillosis infection and/or invasive candidiasis caused by fluconazole-resistant Candida (including Candida krusei) and/or severe infections of the foot caused by actinomycetes bacteria and Fusarium. The compounds and compositions described have a wide range of powerful anti-fungal activity, pharmacokinetic properties and low toxicity.