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Means and methods for the determination of camp in vitro and in vivo
专利权人:
Viacheslav Nikolaev
发明人:
Viacheslav Nikolaev,Moritz Bünemann,Martin J. Lohse
申请号:
US10580027
公开号:
US08889425B2
申请日:
2004.11.26
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Described is a chimeric peptide, comprising, in order, (a) a first detectable label (b) a cAMP binding moiety having only one cAMP binding site and (c) a second detectable label least two detectable labels is describe. The chimeric peptide is useful for direct determination of cAMP concentration in vitro and/or in vivo. Also described are nucleic acids encoding the chimeric peptide, methods of making and modifying the chimeric peptide, a method for determining the cAMP concentration, and kits.
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