An eyedrop delivery system for the automated dispensing of eyedrop solution from bottles and ampoules. The system includes a battery and electronic control circuitry. A sprocket drive motor directs the advancement of a loop cartridge band containing eyedrop solution ampoules, moving each one at a time into position for dispensing. A motor rotates a cam to strike a push rod to compress each ampoule. The system includes an eyelid retracting leg assembly. The cartridge automatically advances the next full ampoule into position for dispensing and pushes the ampoule tip aside. The system helps assure that: (1) a known number of drops are dispensed (2) the dispensed eyedrop(s) fall on the eyeball (by providing eyelid retracting legs to keep the eye open) and (3) the eyedrop(s) landing on the surface of the eye are confirmed using a drop dispensing sensor pair and a surface of the eye sensor pair.