A system is provided for dispensing a fluid. The system has a housing having a fixation means to a user and an orientation element; the cartridge formed so as to be held in a given orientation by the orientation element with respect to the housing; and control means to activate the cartridge to eject a fluid. In one aspect, the system is a emergency rescue fluid(s) transdermal delivery system which includes a removable, single use emergency rescue fluid(s) dispensing cartridge, a wearable device into which the emergency rescue fluid(s) dispensing cartridge uniquely, matingly and removably inserts. The system includes a communication pathway between the wearable device and at least one other cloud network node, and/or at least one communication pathway between the wearable device and at least one GPS network node. In another aspect, the system dispenses a perfume or other fragrance.