УИНТЕРС Джеффри С. (CA),МАНДЕЛЬ Александр Л. (CA),БУРК Элиз Мария Хосе (CA),РИЧ Джеймс Р. (CA),ХСИХ Том ХаньХсяо (CA)
申请号：
RU2016130933
公开号：
RU2016130933A
申请日:
2014.12.29
申请国别(地区):
RU
年份:
2018
代理人:
摘要：
Sulfonamide-containing linkage systems for release of payload compounds from an attached targeting moiety in drug conjugates. The conjugates have the formula of [(P)-(L)]m-(T), wherein (P) is a payload compound, (L) is a linker, (T) is a targeting moiety and m is an integer from 1- to 10. Also provided are pharmaceutical compositions comprising such conjugates and there use in treating cancer.
