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Synthetic glycolipid and use thereof
专利权人:
Takuya Tashiro
发明人:
Takuya Tashiro,Kenji Mori,Masao Shiozaki,Masaru Taniguchi,Hiroshi Watarai
申请号:
US13577159
公开号:
US08853173B2
申请日:
2011.02.04
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A compound represented by the following formula (1):wherein R1 is an aldopyranose residue wherein the 6-hydroxyl group is optionally alkylated, R2 is a C1-26 hydrocarbon group optionally having substituent(s), R3 is a hydrogen atom or a C1-26 hydrocarbon group optionally having substituent(s), R4 is a C1-21 hydrocarbon group optionally having substituent(s), X is an oxygen atom or —CH2—, and Y is —CH2—, —CH(OH)— or —CH═CH—, or a salt thereof is useful for the prophylaxis or treatment of cancer or infection, since it can preferentially induce production of IFN-γ of NKT cells.
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