Novel synthetic glycolipids and their uses

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专利权人:

独立行政法人理化学研究所

发明人:

田代 卓哉,森 謙治,汐崎 正生,谷口 克,渡会 浩志

申请号：

JP2011552842

公开号：

JP5669215B2

申请日:

2011.02.04

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

A compound represented by the following formula (1): wherein R 1 is an aldopyranose residue wherein the 6-hydroxyl group is optionally alkylated, R 2 is a C 1-26 hydrocarbon group optionally having substituent(s), R 3 is a hydrogen atom or a C 1-26 hydrocarbon group optionally having substituent(s), R 4 is a C 1-21 hydrocarbon group optionally having substituent(s), X is an oxygen atom or -CH 2 -, and Y is -CH 2 -, -CH(OH)- or -CH=CH-, or a salt thereof is useful for the prophylaxis or treatment of cancer or infection, since it can preferentially induce production of IFN-³ of NKT cells.

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