An aptamer having an inhibitory activity against NGF is provided. A complex containing an aptamer and a functional substance (for example, an affinity substance, a labeling substance, an enzyme, a drug delivery vehicle, or a drug) having binding activity or inhibitory activity against NGF; having binding activity or inhibitory activity against NGF Provided are a drug, a diagnostic agent, a labeling agent, and the like including an aptamer or a complex containing the aptamer and a functional substance.NGFに対する阻害活性を有するアプタマーを提供する。;NGFに対する結合活性又は阻害活性を有するアプタマー及び機能性物質(例えば、親和性物質、標識用物質、酵素、薬物送達媒体、又は薬物など)を含む複合体;NGFに対する結合活性又は阻害活性を有するアプタマー、又は当該アプタマー及び機能性物質を含む複合体を含む医薬、診断薬及び標識剤などを提供する。