The present invention relates to an aptamer having inhibitory activity against FGF2； a complex comprising an aptamer having binding activity or inhibitory activity against FGF2 and a functional substance (for example, an affinity substance, a labeling substance, an enzyme, a drug delivery vehicle, or a drug) The present invention provides an aptamer having a binding activity or an inhibitory activity for FGF2, or a pharmaceutical, a diagnostic agent and a labeling agent containing a complex containing the aptamer and a functional substance.本発明は、ＦＧＦ２に対する阻害活性を有するアプタマー；ＦＧＦ２に対する結合活性又は阻害活性を有するアプタマー及び機能性物質（例えば、親和性物質、標識用物質、酵素、薬物送達媒体、又は薬物など）を含む複合体；ＦＧＦ２に対する結合活性又は阻害活性を有するアプタマー、又は当該アプタマー及び機能性物質を含む複合体を含む医薬、診断薬及び標識剤；などを提供する。
