대전대학교 산학협력단;주식회사 씨오투바이오;CO2BIO INC.;DAEJEON UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION
发明人:
SONG, GYU YONG,송규용,LEE, JAE IL,이재일,KIM, DONG HEE,김동희,CHOI, HAK JOO,최학주
申请号：
KR1020120009423
公开号：
KR1020130088283A
申请日:
2012.01.31
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A composition containing a flower bud extract of black Panax ginseng is provided to reduce the secretion of atopic dermatitis-inducing factors in cells treated with a mite extract, thereby preventing and treating atopic dermatitis. CONSTITUTION: A pharmaceutical composition for preventing and treating atopic dermatitis contains a flower bud extract of black Panax ginseng as an active ingredient. A method for preparing the flower bud extract of black Panax ginseng comprises the steps of: washing and drying flower buds of 4-7 year old Panax ginseng at 25-65°；C for 12-36 hours； steaming the dried flower buds under the pressure of 0.05-0.45 MPa at 95-155°；C for 3-9 hours； and drying the steamed flower buds at 40-80°；C for 8-16 hours to have a moisture content of 14% or less. The extract is a crude extract (BGFE) or a butanol-soluble extract of black Panax ginseng flower buds. A health food for preventing and treating atopic dermatitis contains the extract as an active ingredient.본 발명은 흑인삼꽃봉오리 추출물을 유효성분으로 함유하는 아토피 질환의 예방 및 치료를 위한 조성물에 관한 것으로, 본 발명의 흑인삼꽃봉오리 추출물은 THP-1 세포에서의 MCP-1, IL-6, IL-8 등의 아토피 유발 인자의 분비를 감소시키는 효능을 나타내므로 아토피질환 치료에 유용한 의약품 및 건강기능식품, 또는 식품첨가물로 이용될 수 있다.
