Methods comprising applying a first analyte point measurement filter comprising: receiving, from an in vivo analyte sensor, at least a first, second, and third uncompensated analyte measurement at a first, second and third reference time； determining a first scaled rate-of-change by multiplying a first weighting coefficient and a first rate-of-change, the first rate-of-change computed between the first uncompensated analyte measurement at the first initial reference time to the second uncompensated analyte measurement at the first prior reference time； determining a second scaled rate-of-change by multiplying a second weighting coefficient and a second rate-of-change, the second rate-of-change computed between the first uncompensated analyte measurement at the first initial reference time to the third uncompensated analyte measurement at the second prior reference time； and calculating a first filter lag-compensated point measurement based on the sum of the first uncompensated analyte measurement, the first scaled rate-of-change, and the second scaled rate-of-change.
