This invention becomes, although the multiplication promotion function of BlyS and APRIL is controlled, the TACI Ig fusion molecule of the sufficient quantity, including the fact that it prescribes to the patient who needs measures, the excessive vegetating disease and the cancer, for example the occurring frequently characteristic marrow swelling and method and the composition in order to deal with the vuarudensutoremumakuroguroburin blood symptom are offered.本発明は、BlyS及びAPRILの増殖促進機能を抑制するのに十分な量のTACI-Ig融合分子を、処置を必要とする患者に投与することを含んで成る、過剰増殖性疾患及び癌、例えば多発性骨髄腫及びヴァルデンストレームマクログロブリン血症を処置するための方法及び組成物を提供する。
