LANGSTON, STEVEN P.,史蒂芬P 兰斯顿,史蒂芬P 蘭斯頓,OLHAVA, EDWARD J.,艾德华J 欧哈维,艾德華J 歐哈維,VYSKOCIL, STEPAN,史戴芬 维斯可希尔,史戴芬 維斯可希爾
申请号：
TW096103917
公开号：
TWI510486B
申请日:
2007.02.02
申请国别(地区):
TW
年份:
2015
代理人:
摘要：
This invention relates to compounds of formula (I) that inhibit E1 activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders and inflammation associated with infection and cachexia.本發明係關於抑制E1活化酶之化合物,包含該化合物之醫藥組合物,及使用該化合物之方法。該化合物可用於治療病症,特別是細胞增生病症,包括癌症、炎性與神經變性病症;以及與感染及惡病質有關聯之發炎。
