Mi-Won Son;Sang-Dug Han;Soon-Hoe Kim;Sang-Kuk Park;Myung-Joo Kang;Sun-Woo Jang;Kyung-Wan Ma
发明人:
Soon-Hoe Kim,Mi-Won Son,Sun-Woo Jang,Sang-Kuk Park,Sang-Dug Han,Myung-Joo Kang,Kyung-Wan Ma
申请号：
US13249513
公开号：
US20130039951A1
申请日:
2011.09.30
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided is a process for preparing a solubilized and stabilized formulation of a sirolimus derivative, which comprises the steps of a dissolving a sirolimus derivative in a solvent, and bring a solution of the sirolimus derivative into contact with a water-soluble carrier to disperse the sirolimus derivative in the water-soluble carrier, and a formulation of a sirolimus derivative with improved solubility and stability as prepared by the preparation process as above.
